Season 15

Diablo 4 Boss Guides

All Diablo 4 bosses for Season 15 — with full drop tables, summoning materials and fight strategies. Pick a boss to see exactly what it drops and how to beat it.

Mythic Uniques

Every Mythic Unique can drop from any of these Uber bosses at the same rate — there is no boss-specific Mythic. On top of that, Mythics can be crafted at the Blacksmith with Resplendent Sparks.

Uber Bosses

Seasonal Bosses Season

Lair Boss Keys

The keys that open Lair Boss Hoards, by tier — with their full in-game details.

Diablo 4 Lair Key Lair Key
Diablo 4 Greater Lair Key Greater Lair Key
Diablo 4 Superior Lair Boss Key Superior Lair Boss Key

Boss Hoards — Required Keys

Since Season 14 you can fight every Uber Boss any time. You only get the loot by opening its Hoard after the kill — which needs the matching key (Belial needs the listed materials instead).

Boss Needed to open
Diablo 4 Varshan Varshan Lair Key1× Lair Key
Diablo 4 Grigoire Grigoire Lair Key1× Lair Key
Diablo 4 Lord Zir Lord Zir Lair Key1× Lair Key
Diablo 4 Beast in Ice Beast in Ice Lair Key1× Lair Key
Diablo 4 Urivar Urivar Lair Key1× Lair Key
Diablo 4 Duriel Duriel Greater Lair Key1× Greater Lair Key
Diablo 4 Andariel Andariel Greater Lair Key1× Greater Lair Key
Diablo 4 Harbinger Harbinger Greater Lair Key1× Greater Lair Key
Diablo 4 Butcher Butcher Greater Lair Key1× Greater Lair Key
Diablo 4 Belial Belial Superior Lair Boss Key1× Superior Lair Boss Key
Diablo 4 Astaroth Astaroth Escalation Sigil1× Escalation Sigil
Diablo 4 Bartuc Bartuc Infernal Hordes Compass1× Infernal Hordes Compass

Where does your loot drop?

Want the full picture of which boss drops what? Our Loot Table lists every item and its sources in one place.

Open the Loot Table →

Frequently Asked Questions

Which bosses are in Diablo 4?

Season 15 has 13 active bosses, 12 of them uber bosses: Varshan, Grigoire, Lord Zir, Beast in Ice, Urivar, Duriel. On top of that there are world bosses, dungeon and legion bosses, and the seasonal boss.

What is the difference between uber bosses and world bosses?

Uber bosses are summoned in their own lair — you need materials or a lair key and can fight them as often as you like. World bosses appear in the open world on a fixed schedule and are fought by everyone present at once.

Which bosses drop Mythic Uniques?

Every uber boss can drop Mythic Uniques, all at the same rate. Only the regular unique loot can be farmed on purpose, and that differs per boss — the loot table shows which boss drops what.

How often can I kill a boss per day?

Uber bosses have no daily limit, they only cost summoning materials. World bosses drop their guaranteed reward cache once per day; further kills only give floor loot.